Induction of Early Atherosclerosis in LDL-Receptor–Deficient Mice Immunized With β2-Glycoprotein I
نویسندگان
چکیده
منابع مشابه
Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I.
BACKGROUND Immunization with beta2-glycoprotein I (beta2GPI), the probable target of autoimmune anticardiolipin antibodies, results in experimental antiphospholipid syndrome in different mouse strains. The present study was undertaken to evaluate the effect of beta2GPI immunization on the progression of atherosclerosis. METHODS AND RESULTS In the first experiment, 3 groups of LDL receptor-def...
متن کاملInduction of Early Atherosclerosis in LDL-Receptor– Deficient Mice Immunized With b2-Glycoprotein I
Background—Immunization with b2-glycoprotein I (b2GPI), the probable target of autoimmune anticardiolipin antibodies, results in experimental antiphospholipid syndrome in different mouse strains. The present study was undertaken to evaluate the effect of b2GPI immunization on the progression of atherosclerosis. Methods and Results—In the first experiment, 3 groups of LDL receptor–deficient (LDL...
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ژورنال
عنوان ژورنال: Circulation
سال: 1998
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.98.11.1108